I have a motto, if it ain't broke, don't fix it.
Deleting the profile seems a bit drastic, how would this affect Calc, Base etc? I'm all for a quiet life, and if there was a chance it would upset something else, it wouldn't be worth it.
We had a similar problem with Sage Accounts. If you modified a report in a certain way, it saved the printer settings within the report, and henceforth, every time you went to print it, it used the report's embedded printer, even if it no longer existed.
I was just wondering if openoffice.org embedded the printer settings into a document in a similar way.